The tagged microarray marker (TAM) method allows high-throughput differentiation between predicted alternative PCR products. Typically, the method is used as a molecular marker approach to determining ...

Identification of the cellular targets of small-molecule hits in phenotypic screens is a central challenge in the development of small molecules as biological tools and potential therapeutics. To ...

RNA interference technology, which is used in cell biology, has revolutionized functional research of the gene products in the last ten years. Now researchers have developed a method which allows a ...

Here, we describe the optimization of a miniaturized cell spot microarray (CSMA) method, which facilitates utilization of the transfection microarray technique for disparate RNAi analyses. To promote ...

Detection of immunogenic proteins remains an important task for life sciences as it nourishes the understanding of pathogenicity, illuminates new potential vaccine candidates and broadens the spectrum ...

High-throughput RNAi screening is widely applied in biological research, but remains expensive, infrastructure-intensive and conversion of many assays to HTS applications in microplate format is not ...

Abstract: Due to the steep price of a microarray experiment, a microarray dataset usually contains a few experimental samples. While the number of experimental samples is small, the number of genes in ...

Microarrays provide a way of organizing biological samples for high-throughput analysis. Samples are arranged in columns and rows upon a support surface consisting of a glass slide, a nitrocellulose ...

Reviewed by Dr. Tomislav Meštrović, MD, Ph.D. The microarray is a very recent development in the field of biotechnology. Scientists are now able to understand the gene functions of any organism by ...

Abstract: In this paper, we discuss the importance of feature subset selection methods in machine learning techniques. An analysis of microarray expression was used to check whether global biological ...